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JOURNAL ARTICLES
Sequential expression and role of Hu RNA-binding proteins during neurogenesis
Y. Wakamatsu, J.A. Weston
Development 1997 124: 3449-3460;

Summary

We have identified three avian (chicken) Hu/elav family RNA-binding protein genes. cHuD and cHuC are expressed specifically in neurons of both the central and peripheral nervous systems. Although cHuA is expressed in a wide variety of tissues, including neurogenic precursor cells, it is transiently down-regulated, and is then re-expressed in maturing neurons. Misexpression of cHuD in cultured neural crest cells results in a dramatic increase in the proportion of cells exhibiting neuronal morphology, molecular markers for neurons, and neurotrophin dependence. These data confirm that cHuD protein is involved in regulating neuronal differentiation.

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JOURNAL ARTICLES
Sequential expression and role of Hu RNA-binding proteins during neurogenesis
Y. Wakamatsu, J.A. Weston
Development 1997 124: 3449-3460;
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