Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Special issues
    • Subject collections
    • Sign up for alerts
  • About us
    • About Development
    • About the Node
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contacts
    • Contacts
    • Subscriptions
    • Feedback
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

User menu

  • Log in
  • Log out

Search

  • Advanced search
Development
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

supporting biologistsinspiring biology

Development

  • Log in
Advanced search

RSS  Twitter  Facebook  YouTube 

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Special issues
    • Subject collections
    • Sign up for alerts
  • About us
    • About Development
    • About the Node
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contacts
    • Contacts
    • Subscriptions
    • Feedback
JOURNAL ARTICLES
Dissection of sexual organ ontogenesis: a genetic analysis of ovule development in Arabidopsis thaliana
K. Schneitz, M. Hulskamp, S.D. Kopczak, R.E. Pruitt
Development 1997 124: 1367-1376;
K. Schneitz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Hulskamp
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S.D. Kopczak
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R.E. Pruitt
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & metrics
  • PDF
Loading

Summary

Understanding organogenesis remains a major challenge in biology. Specification, initiation, pattern formation and cellular morphogenesis, have to be integrated to generate the final three-dimensional architecture of a multicellular organ. To tackle this problem we have chosen the ovules of the flowering plant Arabidopsis thaliana as a model system. In a first step towards a functional analysis of ovule development, we performed a large-scale genetic screen and isolated a number of sterile mutants with aberrant ovule development, We provide indirect genetic evidence for the existence of proximal-distal pattern formation in the Arabidopsis ovule primordium. The analysis of the mutants has identified genes that act at an intermediate regulatory level and control initiation of morphogenesis in response to proximal-distal patterning. A second group of genes functions at a subordinate control level and regulates general cellular processes of morphogenesis. A large group of male and female sterile mutants shows defects restricted to early or late gametogenesis. In addition, we propose that the mature ovule obtains its overall curved shape by at least three different processes that act in only one domain of the ovule.

REFERENCES

    1. Angenent G. C.,
    2. Franken J.,
    3. Busscher M.,
    4. van Dijken A.,
    5. van Went J. L.,
    6. Dons H. J. M.,
    7. van Tunen A. J.
    (1995) A novel class of MADS box genes is involved in ovule development in Petunia. Plant Cell 7, 1569–1582
    OpenUrlAbstract/FREE Full Text
    1. Benavante R. S.,
    2. Skorupska H.,
    3. Palmer R. G.,
    4. Shoemaker R.
    (1989) Embryo sac development in the cv. ks male sterile, female sterile line of soybean (Glycine max). Amer. J. Bot 76, 1759–1768
    OpenUrlCrossRef
    1. Bowman J. L.,
    2. Sakai H.,
    3. Jack T.,
    4. Weigel D.,
    5. Mayer U.,
    6. Meyerowitz E. M.
    (1992) SUPERMAN, a regulator of floral homeotic genes in Arabidopsis. Development 114, 599–615
    OpenUrlAbstract
    1. Coen E. S.,
    2. Meyerowitz E. M.
    (1991) The war of the whorls: genetic interactions controlling flower development. Nature 353, 31–37
    OpenUrlCrossRefPubMedWeb of Science
    1. Colombo L.,
    2. Franken J.,
    3. Koetje E.,
    4. van Went J.,
    5. Dons H. J. M.,
    6. Angenent G. C.,
    7. van Tunen A. J.
    (1995) The petunia MADS box gene FBP11 determines ovule identity. Plant Cell 7, 1859–1868
    OpenUrlAbstract/FREE Full Text
    1. Elliott R. C.,
    2. Betzner A. S.,
    3. Huttner E.,
    4. Oakes M. P.,
    5. Tucker W. Q. J.,
    6. Gerentes D.,
    7. Perez P.,
    8. Smyth D. R.
    (1996) AINTEGUMENTA, an APETALA2 -like gene of Arabidopsis with pleiotropic roles in ovule development and floral organ growth. Plant Cell 8, 155–168
    OpenUrlAbstract/FREE Full Text
    1. Evans P. T.,
    2. Malmberg R. L.
    (1989) Alternative pathways of tobacco placental development: time of commitment and analysis of a mutant. Dev. Biol 136, 273–283
    OpenUrlCrossRefPubMedWeb of Science
    1. Gaiser J. C.,
    2. Robinson-Beers K.,
    3. Gasser C. S.
    (1995) The Arabidopsis SUPERMAN gene mediates asymmetric growth of the outer integument of ovules. Plant Cell 7, 333–345
    OpenUrlAbstract/FREE Full Text
    1. Huang B.-Q.,
    2. Sheridan W. F.
    (1996) Embryo sac development in the maize indeterminate gametophyte1 mutant: abnormal nuclear behavior and defective microtubule organization. Plant Cell 8, 1391–1407
    OpenUrlAbstract/FREE Full Text
    1. Hulskamp M.,
    2. Schneitz K.,
    3. Pruitt R. E.
    (1995) Genetic evidence for a long range activity that directs pollen tube guidance in Arabidopsis. Plant Cell 7, 57–64
    OpenUrlAbstract/FREE Full Text
    1. Jofuku K. D.,
    2. den Boer B. G. W.,
    3. Van Montagu M.,
    4. Okamuro J. K.
    (1994) Control of Arabidopsis flower and seed development by the homeotic gene APETALA2. Plant Cell 6, 1211–1225
    OpenUrlAbstract/FREE Full Text
    1. Kennell J. C.,
    2. Horner H. T.
    (1985) Influence of the soybean male-sterile gene (ms1) on the development of the female gametophyte. Can. J. Genet. Cytol 27, 200–209
    OpenUrl
    1. Kermicle J. L.
    (1971) Pleiotropic effects on seed development of the indeterminate gametophyte gene in maize. Amer. J. Bot 58, 1–7
    OpenUrlCrossRefWeb of Science
    1. Klucher K. M.,
    2. Chow H.,
    3. Reiser L.,
    4. Fischer R. L.
    (1996) The AINTEGUMENTA gene of Arabidopsis required for ovule and female gametophyte development is related to the floral homeotic gene APETALA2. Plant Cell 8, 137–153
    OpenUrlAbstract/FREE Full Text
    1. Lang J. D.,
    2. Ray S.,
    3. Ray A.
    (1994) sin1, a mutation affecting female fertility in Arabidopsis, interacts with mod1, its recessive modifier. Genetics 137, 1101–1110
    OpenUrlAbstract/FREE Full Text
    1. Leon-Kloosterziel K. M.,
    2. Keijzer C. J.,
    3. Koornneef M.
    (1994) A seed shape mutant of Arabidopsis that is affected in integument development. Plant Cell 6, 385–392
    OpenUrlAbstract/FREE Full Text
    1. Lin B.-Y.
    (1978) Structural modifications of the female gametophyte associated with the indeterminate gametophyte (ig) mutant in maize. Can. J. Genet. Cytol 20, 249–257
    OpenUrlCrossRef
    1. Liu Z.,
    2. Meyerowitz E. M.
    (1995) LEUNIG regulates AGAMOUS expression in Arabidopsis flowers. Development 121, 975–991
    OpenUrlAbstract
    1. Ma H.
    (1994) The unfolding drama of flower development: recent results from genetic and molecular analyses. Genes Dev 8, 745–756
    OpenUrlFREE Full Text
    1. Ma H.,
    2. Yanofsky M. F.,
    3. Meyerowitz E. M.
    (1991) AGL1 - ALG6, an Arabidopsis gene family with similarity to floral homeotic and transcription factor genes. Genes Dev 5, 484–495
    OpenUrlAbstract/FREE Full Text
    1. Mansfield S. G.,
    2. Briarty L. G.,
    3. Erni S.
    (1991) Early embryogenesis in Arabidopsis thaliana. I. The mature embryo sac. Can. J. Bot 69, 447–460
    OpenUrlCrossRefWeb of Science
    1. Mayer U.,
    2. Torres Ruiz R. A.,
    3. Berleth T.,
    4. Misera S.,
    5. Jurgens G.
    (1991) Mutations affecting body organization in the Arabidopsis embryo. Nature 353, 402–407
    OpenUrlCrossRef
    1. Modrusan Z.,
    2. Reiser L.,
    3. Feldmann K. A.,
    4. Fischer R. L.,
    5. Haughn G. W.
    (1994) Homeotic transformation of ovules into carpel-like structures in Arabidopsis. Plant Cell 6, 333–349
    OpenUrlAbstract/FREE Full Text
    1. Ray A.,
    2. Robinson-Beers K.,
    3. Ray S.,
    4. Baker S. C.,
    5. Lang J. D.,
    6. Preuss D.,
    7. Milligan S. B.,
    8. Gasser C. S.
    (1994) Arabidopsis floral homeotic gene BELL (BEL1) controls ovule development through negative regulation of AGAMOUS gene (AG). Proc. Natl. Acad. Sci. USA 91, 5761–5765
    OpenUrlAbstract/FREE Full Text
    1. Reiser L.,
    2. Fischer R. L.
    (1993) The ovule and the embryo sac. Plant Cell 5, 1291–1301
    OpenUrlFREE Full Text
    1. Reiser L.,
    2. Modrusan Z. L. M.,
    3. Samach A.,
    4. Ohad N.,
    5. Haughn G. W.,
    6. Fischer R. L.
    (1995) The BELL1 gene encodes a homeodomain protein involved in pattern formation in the Arabidopsis ovule primordium. Cell 83, 735–742
    OpenUrlCrossRefPubMedWeb of Science
    1. Robinson-Beers K.,
    2. Pruitt R. E.,
    3. Gasser C. S.
    (1992) Ovule development in wild-type Arabidopsis and two female-sterile mutants. Plant Cell 4, 1237–1249
    OpenUrlAbstract/FREE Full Text
    1. Rounsley S. D.,
    2. Ditta G. S.,
    3. Yanofsky M. F.
    (1995) Diverse roles for MADS box genes in Arabidopsis development. Plant Cell 7, 1259–1269
    OpenUrlAbstract/FREE Full Text
    1. Sakai H.,
    2. Medrano L. J.,
    3. Meyerowitz E. M.
    (1995) Role of SUPERMAN in maintaining Arabidopsis floral whorl boundaries. Nature 378, 199–203
    OpenUrlCrossRefPubMedWeb of Science
    1. Savidge B.,
    2. Rounsley S. D.,
    3. Yanofsky M.
    (1995) Temporal relationship between the transcription of two Arabidopsis MADS box genes and the floral organ identity genes. Plant Cell 7, 721–733
    OpenUrlAbstract/FREE Full Text
    1. Schneitz K.,
    2. Hulskamp M.,
    3. Pruitt R. E.
    (1995) Wild-type ovule development in Arabidopsis thaliana: a light microscope study of cleared whole-mount tissue. Plant J 7, 731–749
    OpenUrlCrossRefWeb of Science
    1. Weigel D.
    (1995) The APETALA2 domain is related to a novel type of DNA binding domain. Plant Cell 7, 388–389
    OpenUrlFREE Full Text
    1. Weigel D.,
    2. Meyerowitz E. M.
    (1994) The abcs of floral homeotic genes. Cell 78, 203–209
    OpenUrlCrossRefPubMedWeb of Science
Previous ArticleNext Article
Back to top
Previous ArticleNext Article

This Issue

 Download PDF

Email

Thank you for your interest in spreading the word on Development.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Dissection of sexual organ ontogenesis: a genetic analysis of ovule development in Arabidopsis thaliana
(Your Name) has sent you a message from Development
(Your Name) thought you would like to see the Development web site.
Share
JOURNAL ARTICLES
Dissection of sexual organ ontogenesis: a genetic analysis of ovule development in Arabidopsis thaliana
K. Schneitz, M. Hulskamp, S.D. Kopczak, R.E. Pruitt
Development 1997 124: 1367-1376;
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
JOURNAL ARTICLES
Dissection of sexual organ ontogenesis: a genetic analysis of ovule development in Arabidopsis thaliana
K. Schneitz, M. Hulskamp, S.D. Kopczak, R.E. Pruitt
Development 1997 124: 1367-1376;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Alerts

Please log in to add an alert for this article.

Sign in to email alerts with your email address

Article navigation

  • Top
  • Article
  • Info & metrics
  • PDF

Related articles

Cited by...

More in this TOC section

  • Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice
  • The dermomyotome dorsomedial lip drives growth and morphogenesis of both the primary myotome and dermomyotome epithelium
  • REF-1, a protein with two bHLH domains, alters the pattern of cell fusion in C. elegans by regulating Hox protein activity
Show more JOURNAL ARTICLES

Similar articles

Other journals from The Company of Biologists

Journal of Cell Science

Journal of Experimental Biology

Disease Models & Mechanisms

Biology Open

Advertisement

The people behind the papers – George Britton and Aryeh Warmflash

George and Aryeh

First author George Britton and his supervisor Aryeh Warmflash discuss their new Development paper in which they apply advanced in vitro culturing techniques to investigate embryonic ectoderm patterning.


Travelling Fellowship – New imaging approach unveils a bigger picture

Highlights from Travelling Fellowship trips

Find out how Pamela Imperadore’s Travelling Fellowship grant from The Company of Biologists took her to Germany, where she used new imaging techniques to investigate the cellular machinery underlying octopus arm regeneration. Don’t miss the next application deadline for 2020 travel, coming up on 29 November. Where will your research take you?


Primer – Principles and applications of optogenetics in developmental biology

Schematic demonstrating the approaches to controlling protein activity using optogenetics.

Protein function can be controlled by light using optogenetic techniques. In their new Primer, Stefano De Renzis and his colleagues in Heidelberg provide an overview of the most commonly used optogenetic tools and their application in developmental biology.


preLights – Self-organised symmetry breaking in zebrafish reveals feedback from morphogenesis to pattern formation

Sundar Naganathan

preLighter Sundar Naganathan explains his selected preprint by Vikas Trivedi, Benjamin Steventon and their co-workers on pescoids, a new in vitro model system to study early zebrafish embryogenesis.


Spotlight – Can laboratory model systems instruct human limb regeneration?

An extract from a schematic demonstrating the possible pipeline for how discovery in lab model systems can influence applications for regenerative therapies.

One of the most challenging objectives of tissue regeneration research is regrowth of a lost or amputated limb. Here, Ben Cox, Maximina Yun and Kenneth Poss outline the research avenues yet to be explored to move closer to this capstone achievement.


Articles of interest in our sister journals

Tox4 modulates cell fate reprogramming

Lotte Vanheer, Juan Song, Natalie De Geest, Adrian Janiszewski, Irene Talon, Caterina Provenzano, Taeho Oh, Joel Chappell, Vincent Pasque
Journal of Cell Science

Drosophila melanogaster: a simple system for understanding complexity

Stephanie E. Mohr, Norbert Perrimon
Disease Models & Mechanisms

Articles

  • Accepted manuscripts
  • Issue in progress
  • Latest complete issue
  • Issue archive
  • Archive by article type
  • Special issues
  • Subject collections
  • Sign up for alerts

About us

  • About Development
  • About the Node
  • Editors and board
  • Editor biographies
  • Travelling Fellowships
  • Grants and funding
  • Journal Meetings
  • Workshops
  • The Company of Biologists

For authors

  • Submit a manuscript
  • Aims and scope
  • Presubmission enquiries
  • Article types
  • Manuscript preparation
  • Cover suggestions
  • Editorial process
  • Promoting your paper
  • Open Access
  • Biology Open transfer

Journal info

  • Journal policies
  • Rights and permissions
  • Media policies
  • Reviewer guide
  • Sign up for alerts

Contact

  • Contact Development
  • Subscriptions
  • Advertising
  • Feedback

 Twitter   YouTube   LinkedIn

© 2019   The Company of Biologists Ltd   Registered Charity 277992