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JOURNAL ARTICLES
Redundant regulation of meristem identity and plant architecture by FRUITFULL, APETALA1 and CAULIFLOWER
C. Ferrandiz, Q. Gu, R. Martienssen, M.F. Yanofsky
Development 2000 127: 725-734;

Summary

The transition from vegetative to reproductive phases during Arabidopsis development is the result of a complex interaction of environmental and endogenous factors. One of the key regulators of this transition is LEAFY (LFY), whose threshold levels of activity are proposed to mediate the initiation of flowers. The closely related APETALA1 (AP1) and CAULIFLOWER (CAL) meristem identity genes are also important for flower initiation, in part because of their roles in upregulating LFY expression. We have found that mutations in the FRUITFULL (FUL) MADS-box gene, when combined with mutations in AP1 and CAL, lead to a dramatic non-flowering phenotype in which plants continuously elaborate leafy shoots in place of flowers. We demonstrate that this phenotype is caused both by the lack of LFY upregulation and by the ectopic expression of the TERMINAL FLOWER1 (TFL1) gene. Our results suggest that the FUL, AP1 and CAL genes act redundantly to control inflorescence architecture by affecting the domains of LFY and TFL1 expression as well as the relative levels of their activities.

REFERENCES

    1. Alvarez J.,
    2. Guli C. L.,
    3. Yu X.-H.,
    4. Smyth D. R.
    (1992) terminal flower, a gene affecting inflorescence development in Arabidopsis thaliana. Plant J 2, 103–116
    1. Aukerman M. J.,
    2. Lee I.,
    3. Weigel D.,
    4. Amasino R.
    (1999) The Arabidopsis flowering-time gene LUMINIDEPENDENS is expressed primarily in regions of cell proliferation and encodes a nuclear protein that regulates LEAFY expression. Plant J 18, 195–203
    OpenUrlCrossRefPubMedWeb of Science
    1. Blázquez M. A.,
    2. Soowal L.,
    3. Lee I.,
    4. Weigel D.
    (1997) LEAFY expression and flower initiation in Arabidopsis. Development 124, 3835–3844
    OpenUrlAbstract
    1. Bowman J. L.,
    2. Alvarez J.,
    3. Weigel D.,
    4. Meyerowitz E. M.,
    5. Smyth D. R.
    (1993) Control of flower development in Arabidopsis thaliana by APETALA1 and interacting genes. Development 119, 721–743
    OpenUrlAbstract/FREE Full Text
    1. Bradley D. J.,
    2. Ratcliffe O. J.,
    3. Vincent C.,
    4. Carpenter R.,
    5. Coen E. S.
    (1997) Inflorescence commitment and architecture in Arabidopsis. Science 275, 80–83
    OpenUrlAbstract/FREE Full Text
    1. Drews G. N.,
    2. Bowman J. L.,
    3. Meyerowitz E. M.
    (1991) Negative regulation of the Arabidopsis homeotic gene AGAMOUS by the APETALA2 product. Cell 65, 991–1002
    OpenUrlCrossRefPubMedWeb of Science
    1. Gu Q.,
    2. Ferrándiz C.,
    3. Yanofsky M. F.,
    4. Martienssen R.
    (1998) The FRUITFULL MADS-box gene mediates cell differentiation during Arabidopsis fruit development. Development 125, 1509–1517
    OpenUrlAbstract
    1. Hempel F. D.,
    2. Weigel D.,
    3. Mandel M. A.,
    4. Ditta G.,
    5. Zambryski P.,
    6. Feldman L. J.,
    7. Yanofsky M. F.
    (1997) Floral determination and expression of floral regulatory genes in Arabidopsis. Development 124, 3845–3853
    OpenUrlAbstract
    1. Huala E.,
    2. Sussex I. M.
    (1992) LEAFY interacts with floral homeotic genes to regulate Arabidopsis floral development. Plant Cell 4, 901–913
    OpenUrlAbstract/FREE Full Text
    1. Irish V. F.,
    2. Sussex I. M.
    (1990) Function of the apetala-1 gene during Arabidopsis floral development. Plant Cell 2, 741–751
    OpenUrlAbstract/FREE Full Text
    1. Jack T.,
    2. Brockman L. L.,
    3. Meyerowitz E. M.
    (1992) The homeotic gene APETALA3 of Arabidopsis thaliana encodes a MADS-box and is expressed in petals and stamens. Cell 68, 683–697
    OpenUrlCrossRefPubMedWeb of Science
    1. Kempin S. A.,
    2. Savidge B.,
    3. Yanofsky M. F.
    (1995) Molecular basis of the cauliflower phenotype in Arabidopsis. Science 267, 522–525
    OpenUrlAbstract/FREE Full Text
    1. Lee I.,
    2. Wolfe D. S.,
    3. Nilsson O.,
    4. Weigel D.
    (1997) A LEAFY co-regulator encoded by UNUSUAL FLORAL ORGANS. Curr. Biol 7, 95–104
    OpenUrlCrossRefPubMedWeb of Science
    1. Liljegren S.,
    2. Gustafson-Brown C.,
    3. Pinyopich A.,
    4. Ditta G.,
    5. Yanofsky M.
    (1999) Interactions among the meristem identity genes APETALA1, LEAFY and TERMINAL FLOWER specify meristem fate. Plant Cell 11, 1007–1018
    OpenUrlAbstract/FREE Full Text
    1. Mandel M. A.,
    2. Gustafson-Brown C.,
    3. Savidge B.,
    4. Yanofsky M. F.
    (1992) Molecular characterization of the Arabidopsis floral homeotic gene APETALA1. Nature 360, 273–277
    OpenUrlCrossRefPubMedWeb of Science
    1. Mandel M. A.,
    2. Yanofsky M. F.
    (1995) The Arabidopsis AGL8 MADS box gene is expressed in inflorescence meristems and is negatively regulated by APETALA1. Plant Cell 7, 1763–1771
    OpenUrlAbstract/FREE Full Text
    1. Mandel M. A.,
    2. Yanofsky M. F.
    (1995) A gene triggering flower development in Arabidopsis. Nature 377, 522–524
    OpenUrlCrossRefPubMedWeb of Science
    1. Mizukami Y.,
    2. Ma H.
    (1992) Ectopic expression of the floral homeotic gene AGAMOUS in transgenic Arabidopsis plants alters floral organ identity. Cell 71, 119–131
    OpenUrlCrossRefPubMedWeb of Science
    1. Mizukami Y.,
    2. Ma H.
    (1997) Determination of Arabidopsis floral meristem identity by AGAMOUS. Plant Cell 9, 393–408
    OpenUrlAbstract/FREE Full Text
    1. Neff M.,
    2. Neff J.,
    3. Chory J.,
    4. Pepper A.
    (1998) dCAPS, a simple technique for the genetic analysis of single nucleotide polymorphisms:experimental aplications in Arabidopsis thaliana genetics. Plant J 14, 387–392
    OpenUrlCrossRefPubMedWeb of Science
    1. Piñeiro M.,
    2. Coupland G.
    (1998) The control of flowering time and floral identity in Arabidopsis. Plant Physiol 117, 1–8
    OpenUrlFREE Full Text
    1. Poethig R. S.
    (1990) Phase changes and the regulation of shoot morphogenesis in plants. Science 250, 923–930
    OpenUrlAbstract/FREE Full Text
    1. Ratcliffe O.,
    2. Bradley D.,
    3. Coen E.
    (1999) Separation of shoot and floral identity in Arabidopsis. Development 126, 1109–1120
    OpenUrlAbstract
    1. Ruiz-García L.,
    2. Madueño F.,
    3. Wilkinson M.,
    4. Haughn G.,
    5. Salinas J.,
    6. Martínez-Zapater J. M.
    (1997) Different roles of flowering time genes in the activation of floral initiation genes in Arabidopsis. Plant Cell 9, 1921–1934
    OpenUrlAbstract/FREE Full Text
    1. Schultz E. A.,
    2. Haughn G. W.
    (1991) LEAFY, a homeotic gene that regulates inflorescence development in Arabidopsis. Plant Cell 3, 771–781
    OpenUrlAbstract/FREE Full Text
    1. Shannon S.,
    2. Meeks-Wagner D. R.
    (1991) A mutation in the Arabidopsis TFL1 gene affects inflorescence meristem development. Plant Cell 3, 877–892
    OpenUrlAbstract/FREE Full Text
    1. Shannon S.,
    2. Meeks-Wagner D. R.
    (1993) Genetic interactions that regulate inflorescence development in Arabidopsis. Plant Cell 5, 639–655
    OpenUrlAbstract/FREE Full Text
    1. Smyth D. R.,
    2. Bowman J. L.,
    3. Meyerowitz E. M.
    (1990) Early flower development in Arabidopsis. Plant Cell 2, 755–767
    OpenUrlAbstract/FREE Full Text
    1. Weigel D.,
    2. Alvarez J.,
    3. Smyth D. R.,
    4. Yanofsky M. F.,
    5. Meyerowitz E. M.
    (1992) LEAFY controls floral meristem identity in Arabidopsis. Cell 69, 843–859
    OpenUrlCrossRefPubMedWeb of Science
    1. Weigel D.,
    2. Nilsson O.
    (1995) A developmental switch sufficient for flower initiation in diverse plants. Nature 377, 495–500
    OpenUrlCrossRefPubMedWeb of Science
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JOURNAL ARTICLES
Redundant regulation of meristem identity and plant architecture by FRUITFULL, APETALA1 and CAULIFLOWER
C. Ferrandiz, Q. Gu, R. Martienssen, M.F. Yanofsky
Development 2000 127: 725-734;
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