DEV00627 Supplemental Data

Files in this Data Supplement:

• Supplemental Figure 1 - Sequence alignments of different hairy/E(spl) proteins. Conservation levels are indicated by different degrees of background shading, with black indicating the highest conservation. c, Gallus domesticus; dr, Danio rerio; hs, Homo sapiens; mm, Mus musculus; xl, Xenopus laevis.
• Supplemental Figure 2 - Expression pattern of her7 in different developmental stages. (A) Shield stage; (B) 70% epiboly; (C) 75% epiboly; (D) 80% epiboly; (E-G) 95% epiboly; (H) 1-, (I) 14- and (J) 18-somite stages; (K) 6-somite stage; (L) 6+-somite stage; (M) 6++-somite stage; (N) early 7-somite stage. (A-N) Dorsal views. (I,K-N) Flat-mounted embryos, anterior towards the top. Arrow in A indicates the embryonic shield devoid of her7 transcript. Arrowheads in E,G,I indicate the weak her7 expression in the anterior-most stripe. This stripe is consistently stronger in her1 stained embryos (compare with M�ller et al. 1996). *, + and # in K-N indicate consecutive stripes of her7 expression during one cycle of somite formation.