This issue is currently being compiled. Articles in their final version of record are published here as soon as they are ready. The most recent articles appear at the top of the relevant section. More information on our new continuous publication model can be found here.
RESEARCH HIGHLIGHT
REVIEWS
- Diversity and robustness of bone morphogenetic protein pattern formation
Summary: This Review looks at BMP morphogen gradient patterning in diverse developmental contexts including in Tribolium, Drosophila, Xenopus and zebrafish early embryos, as well as the Drosophila wing imaginal disc and germarium.
- The origin and mechanisms of smooth muscle cell development in vertebrates
Summary: A review of the developmental origin of smooth muscle cells within different tissues and the instructive roles of smooth muscle in development.
- Self-organized cell migration across scales – from single cell movement to tissue formation
Summary: This Review discusses principles of self-organization that govern the initiation, maintenance and directionality of efficient migration in single and collective cells, independently of external regulators.
RESEARCH REPORT
- Electrostatic plasma membrane targeting contributes to Dlg function in cell polarity and tumorigenesis
Highlighted Article: Dlg contains a positively charged polybasic domain that electrostatically binds plasma membrane phosphoinositides, which is crucial for Dlg to regulate both polarity and tumorigenesis.
RESEARCH ARTICLE
- An early global role for Axin is required for correct patterning of the anterior-posterior axis in the sea urchin embryo
Summary: Axin function is required in the early sea urchin embryo to regulate nuclear β-catenin levels and prevent ectopic cell fates in multipotent early blastomeres, and to ensure correct anterior-posterior axis patterning.
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Upcoming special issue: call for papers
The Immune System in Development and Regeneration
Guest editors: Florent Ginhoux and Paul Martin
Submission deadline: 1 September 2021
Publication: Spring 2022
The special issue welcomes Review articles as well as Research articles, and will be widely promoted online and at key global conferences.
The people behind the papers - Clément Dubois, Shivam Gupta, Andrew Mugler and Marie-Anne Félix
A new paper investigates the robustness of neuroblast migration in the C. elegans larva in the face of both genetic and environmental variation. In an interview, the paper's four authors tell us more about the story.
Development presents...
Our successful webinar series continues into 2021, with early-career researchers presenting their papers and a chance to virtually network with the developmental biology community afterwards. Every talk is recorded and since launching in August last year, the series has clocked up almost 10k views on YouTube.
Here, Swann Floc'hlay discusses her work modelling dorsal-ventral axis specification in the sea urchin embryo.
Save your spot at our next session:
14 April
Time: 17:00 BST
Chaired by: François Guillemot
12 May
Time: TBC
Chaired by: Paola Arlotta
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