RT Journal Article
SR Electronic
T1 Presence of basic fibroblast growth factor in the early embryo
JF Development
JO Development
FD The Company of Biologists Limited
SP 147
OP 153
VO 105
IS 1
A1 Slack, J.M.W.
A1 Isaacs, H.V.
YR 1989
UL http://dev.biologists.org/content/105/1/147.abstract
AB Mesoderm-inducing activity can be extracted from eggs or whole ovary. It binds to heparin and can be heparin or anti-bFGF but not by anti-TGFbeta. Two be identified by Western blotting and have molecular 19 and 14K. The content in embryos is about 7unitsg-1 7ngml-1) which would be sufficient for it to be acting inducer of ventral mesoderm. Attempts to detect