Table 1.

Expression of GFP in independent lines of E11.5 transgenic mouse embryos containing wild-type and mutant derivates of M250 linked to theΔ NheI:GFP construct

Total number of transgenic embryosNumber of embryos with GFP+ motoneurons (%)
Wild type54 (80.0)
E box mt122 (16.7)
A/T mt61* (16.7)
  • * A small number of weak GFP+ motoneurons were detected per section. This embryo was selected for the image in Fig. 4L