Table 2.

Decreased transcripts in the trigeminal ganglion of Brn3a mutant mouse embryos

DescriptionFold Knockout/control
GenBank acc no. Experiment 1 Experiment 2
Decreased transcriptsWild typeHeterozygoteKnockoutWild typeHeterozygoteKnockout
NPY1 receptorZ18280474242594896351521.4
HoxD1 (Hox-4.9) (2 probe sets)M878027237133883776519311.6
AdvillinAF04144814551407242202218621957.9
Na+ channel Scn6aL3617921131625220240726.8
BasonuclinU8806445042680796589896.6
Homeobox transcription factor Hmx1AF009614612542102682728946.6
Phospholipase A2 group VIIU3427730032149604457936.0
Runt related transcription factor Runx1D265327427211267207401495.3
PACAPAB010149880697175126113182265.1
K+ channel Kcnab2U655921019827289175010832214.8
GalaninL3858040883753938381640939524.2
Olfactomedin 1 (noelin, pancortin)D7826512161250390149412483863.4
Bicarbonate transporter SLC4A4AF020195369375163382288763.4
Insulin-like growth factor binding protein 5 Igfbp5L1244796831027822837560686432103.3
Myotubularin related protein 7AF073882370526976865283253.2
Apolipoprotein ED00466185714044052029269410863.1
FK506 binding protein 1bAF0608729309886630415809716520713.1
Hivep2Y159074133731284634771672.9
LatexinD8876910051181402181615966282.7
HLH transcription factor Id1M3188511601003366125912105022.7
Synaptotagmin 1D377924122441115635692422.6
Na+ channel Scn9aL423382604261405664121782.6
C-kitY008647024842638477953042.5
Elongation factor 1 alpha 2L264793197325813263248308113052.4
Tyrosine hydroxylaseM692003078330413913375412615632.3
RNA polymerase II 3D839991455115952699712185022.3
Synuclein, gammaAF0172557459945832098466814540842.3
Activated leukocyte cell adhesion moleculeL2527413201574555199817279812.3
Peripherin 1X154753746456320096947698228582.3
Annexin A2M14044944411497416490511226856392.2
Fgfl 3AF020737926113746193210554632.2
  • Transcripts were selected from among 5993 known genes on the U74aV2 chip according to the criteria described in Table 1. The threshold change-p value for decreased transcripts is pΔ >0.997. The fold change is calculated as the ratio of control/knockout expression.