Table 2.

The effect of FrdMO and DprMO on neural plate closure

Phenotypes (%)
Experimental groupsDose/embryon*NormalOpen neural plate
Control MO8 ng45937
FrdMO8 ng422179
DprMO4 ng532872
FrdMO+Frodo8 ng+1 ng406238
FrdMO+βcat8 ng+10 pg42793
  • Eight- to sixteen-cell stage embryos were injected with MOs and RNAs as indicated above into the right animal-dorsal blastomere. Phenotypes were scored morphologically at stages 18-20.

    The data were obtained from two separate experiments.

  • * Number of scored embryos