Table 1.

Names of core components of Notch signaling (ligand, receptor and transcription factor) in different species

Core componentC. elegansD. melanogasterMammals
LigandLAG-2DeltaDelta-like1 (DLL1)
APX-1SerrateDelta-like2 (DLL2)
ARG-2Delta-like3 (DLL3)
F16B12.2Jagged 1 (JAG1)
Jagged 2 (JAG2)
Receptor (Notch)LIN-12NotchNotch1
GLP-1Notch2
Notch3
Notch4
Transcription factor (CSL)LAG-1Suppressor of Hairless [Su(H)]CBF1/RBPJκ
RBPL