In vitro analysis of early dorsal bud formation
| Wild type (n) | Cdh2−/− (n) | Cdh2−/− + plasma (n) | Cdh2−/− + S1P (n) | Cdh2−/− + PTX + S1P (n) | WT + PTX (n) | |
|---|---|---|---|---|---|---|
| db | 20 (21) | 3 (18) | 5 (10) | 9 (14) | 2 (6) | 7 (10) |
| % db* | 95% | 17% | 50% | 64% | 33% | 70% |
db, early dorsal bud formation.
↵* Percentage of explants that develop a dorsal bud in addition to a ventral bud.