Table 2.

Expression of lateral neural markers depends upon Nodal signalling

Control SB431542tALK4/5/7 Nodal-MO
%n e %n e %n e %n e
Ci-Chordin 100 1517 0 683 32 * 312 0 312
Ci-HES-b 100 2687 0 392 38 * 342 4 263
Ci-FGF8/17/18 95 1615 0 442 0 191 0 222
Ci-Lefty 99 1084 2 432ND 0 312
Ci-ChAT 97 1526 5 * 612 3 * 382 0 232
Ci-HB9/MNX 93 1806 0 522 6 * 342 0 302
Ci-Actin 93 884 2.5 402ND 11.5 262
  • Numbers in bold indicate percentage (%) of embryos showing expression in the lateral neural plate (Ci-Chordin, Ci-HES-b, Ci-FGF8/17/18 and Ci-Lefty), presumptive motoneurones (Ci-ChAT and Ci-HB9/MNX) or secondary muscle lineage (Ci-Actin) following the treatment indicated at the top.

  • * , most of these embryos showed reduced expression.

  • n , number of embryos analysed.

  • e , number of independent experiments.