Table 2.

Recovery of conceptuses from intercross matings of TC/+ mice

Age
Genotype∼6.75 dpc n (%)∼7.5 dpc n (%)∼8.0 dpc n (%)∼8.5 dpc n (%)∼9.0 dpc n (%)∼9.5 dpc n (%)∼10.5 dpc n (%)∼13.5 dpc n (%)
+/+14 (25.0)31 (22.5)123 (25.7)31 (23.8)7 (31.8)3 (27.3)6 (31.6)4 (20.0)
TC/+24 (42.9)68 (49.3)234 (49.0)56 (43.1)8 (36.4)7 (63.6)8 (42.1)8 (40.0)
TC/TC13 (23.2)32 (23.2)96 (20.1)38 (29.2)7 (31.8)1 (9.1)00
Resorptions5 (8.9)7 (5.0)25 (5.2)5 (3.8)005* (26.3)8† (40.0)
Number of litters61754203322
  • All genotypes were confirmed by PCR. For all stages the expected percentage of +/+, TC/+ and TC/TC conceptuses was 25%, 50% and 25%, respectively. Where possible (from ∼10.5-13.5 dpc), resorbing conceptuses were genotyped. Death of the conceptus was defined as absence of heart beat.

  • * One TC/+ conceptus was dead and resorbing; all other dead, resorbing conceptuses were TC/TC.

  • Two TC/+ conceptuses were dead and resorbing; all other dead, resorbing conceptuses were TC/TC.