Table 1.

Tissue wet-weight, DA and DOPAC content in the forebrain of Ngn2 mutant mice

Wild type (n=6)Ngn2-/- (n=4)
Weight (mg)305±4231±5 (75%)*
DA total (pmol)1207±33458±48 (38%)*
DOPAC total (pmol)185±1388±8 (48%)*
DOPAC/DA ratio0.150.19
DA concentration (pmol/mg)3.96±0.111.99±0.14 (50%)*
DOPAC concentration (pmol/mg)0.61±0.030.38±0.02 (62%)*
  • The percentage of wild-type value is shown in parentheses.

  • * Statistical significance at P<0.01 (unpaired Student's t-test)