Table 1.

Genotypes of offspring from heterozygote knock-in (KI) intercrosses at late embryonic and postnatal stages

AgeLinen+/+ (%)+/KI (%)KI/KI (%)
P4-P7wtKI #17224 (33)36 (50)12 (17)
wtKI #2319 (29)20 (65)2 (6)
ΔFrs6018 (30)42 (70)0
E16.5wtKI #2247 (29)13 (54)4 (17)
wtKI #3174 (24)10 (59)3 (18)
ΔFrs224 (18)17 (77)1 (5)
  • wtKI #1-3 are KI mouse lines derived from independently targeted ES cell clones.