Armadillo
- Phosphorylation potential of Drosophila E-Cadherin intracellular domain is essential for development and adherens junction biosynthetic dynamics regulation
Summary: Phosphorylations of the conserved serine cluster in the Drosophila E-Cadherin intracellular tail are quantitatively rather than site specifically required for its function in adherens junction formation.
- Innexin7a forms junctions that stabilize the basal membrane during cellularization of the blastoderm in Tribolium castaneum
Highlighted article: Cellularization in the embryo of the beetle Tribolium requires the junction protein Innexin7a, which links the basal membrane to the yolk membrane. This mechanism is distinct from that in Drosophila.
- Girdin-mediated interactions between cadherin and the actin cytoskeleton are required for epithelial morphogenesis in Drosophila
SUMMARY: The cytoskeletal adaptor protein Girdin physically and functionally interacts with cadherin-catenin complex components to regulate adherens junctions and hence cell adhesion during Drosophila embryogenesis.