Dand5
- Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse
Summary: Single and double mutants generated in the zebrafish nodal, lefty1 and cerl2/dand5 genes reveal that the mechanisms of left-right patterning are highly conserved between zebrafish and mouse.
- Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP, TGFβ and Wnt signaling
Highlighted article: The exposure of hESCs to IGF1 and to COCO, which inhibits BMP, TGFβ and Wnt signaling pathways, efficiently differentiates them into functional cone photoreceptors.