Dauer
- ENPL-1, the Caenorhabditis elegans homolog of GRP94, promotes insulin secretion via regulation of proinsulin processing and maturation
Summary: Understanding the roles of ER chaperones in cell biology is of great interest. This Research article shows that ENPL-1 promotes insulin secretion in Caenorhabditis elegans via regulation of proinsulin processing.
- A histone H4 lysine 20 methyltransferase couples environmental cues to sensory neuron control of developmental plasticity
Summary: The C. elegans histone methyltransferase SET-4 acts to link environmental signals to diapause through regulation of the X-linked insulin-like peptide gene ins-9 in sensory neurons.