Epigenetic
- Hallmarks of intestinal stem cells
Summary: In this Review, we discuss recent insight into the molecular identity of the intestinal stem cells, including their signalling crosstalk, proliferation and epigenetic and metabolic states, and their role during development and regeneration.
- H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration
Summary: Abnormal sarcomere persistence is a significant barrier to heart regeneration in zebrafish. Dampening expression of similar structural components in the human heart might improve its regenerative capacity.