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Fat

  • PRIMER
    Planar cell polarity: two genetic systems use one mechanism to read gradients
    Peter A. Lawrence, José Casal
    Development 2018 145: dev168229 doi: 10.1242/dev.168229 Published 10 December 2018

    Summary: The key molecules responsible for planar cell polarity form bridges that span between neighbouring cells. Gradients across the tissue cause these bridges to be asymmetrically localised within each cell.

  • STEM CELLS AND REGENERATION
    Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching
    Yaopan Mao, Philippa Francis-West, Kenneth D. Irvine
    Development 2015 142: 2574-2585; doi: 10.1242/dev.122630

    Highlighted article: In mice, kidney morphogenesis and size of the nephron progenitor pool are regulated by Fat4-Dchs1 signaling between stromal cells and nephron progenitors, independently of YAP.

  • RESEARCH REPORTS
    The ubiquitin ligase FbxL7 regulates the Dachsous-Fat-Dachs system in Drosophila
    Mariana Rodrigues-Campos, Barry J. Thompson
    Development 2014 141: 4098-4103; doi: 10.1242/dev.113498
  • RESEARCH ARTICLES
    Regulation of long-range planar cell polarity by Fat-Dachsous signaling
    Praveer Sharma, Helen McNeill
    Development 2013 140: 3869-3881; doi: 10.1242/dev.094730
  • RESEARCH ARTICLES
    Signal transduction by the Fat cytoplasmic domain
    Guohui Pan, Yongqiang Feng, Abhijit A. Ambegaonkar, Gongping Sun, Matthew Huff, Cordelia Rauskolb, Kenneth D. Irvine
    Development 2013 140: 831-842; doi: 10.1242/dev.088534
  • RESEARCH ARTICLES
    Regulation of cytoskeletal organization and junctional remodeling by the atypical cadherin Fat
    Emily Marcinkevicius, Jennifer A. Zallen
    Development 2013 140: 433-443; doi: 10.1242/dev.083949

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