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fate map

  • TECHNIQUES AND RESOURCES
    Developmental analyses of mouse embryos and adults using a non-overlapping tracing system for all three germ layers
    Takashi Serizawa, Ayako Isotani, Takafumi Matsumura, Katsuyuki Nakanishi, Shigenori Nonaka, Shinsuke Shibata, Masahito Ikawa, Hideyuki Okano
    Development 2019 146: dev174938 doi: 10.1242/dev.174938 Published 4 November 2019

    Highlighted Article: We have developed a new transgenic technique for simultaneous labelling of all three germ layers in mice that overcomes the difficulties of conventional single-gene tracing systems in precision lineage tracing.

  • HUMAN DEVELOPMENT
    Mapping cell migrations and fates in a gastruloid model to the human primitive streak
    Iain Martyn, Eric D. Siggia, Ali H. Brivanlou
    Development 2019 146: dev179564 doi: 10.1242/dev.179564 Published 12 September 2019

    Highlighted Article: Comparative analysis of human gastruloids along with recording of cell migrations enables the piecing together of part of a rudimentary fate map for the human primitive streak.

  • RESEARCH ARTICLE
    A mesodermal fate map for adipose tissue
    Zachary L. Sebo, Elise Jeffery, Brandon Holtrup, Matthew S. Rodeheffer
    Development 2018 145: dev166801 doi: 10.1242/dev.166801 Published 17 August 2018

    Highlighted Article: Embryonic cell lineage tracing of adipose tissue reveals that perigonadal fat arises from distinct mesodermal subcompartments in males and females, and that <50% of interscapular brown fat arises from central dermomyotome.

  • RESEARCH ARTICLE
    A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons
    Navid Nouri, Rajeshwar Awatramani
    Development 2017 144: 916-927; doi: 10.1242/dev.144949

    Summary: A novel boundary that subdivides the mouse mesodiencephalic floor plate into two microdomains, each giving rise to distinct types of neurons, is identified.

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