Fgf
- Pineal progenitors originate from a non-neural territory limited by FGF signalling
Highlighted Article: Gene expression and fate mapping/lineage tracing in zebrafish reveals that the pineal organ develops from the non-neural pre-placodal ectoderm under the control of FGF signalling.
- N-cadherin stabilises neural identity by dampening anti-neural signals
Summary: As pluripotent cells undergo neural differentiation they swap E-cadherin for N-cadherin. This switch in adhesion molecules modulates signalling in order to facilitate the differentiation process.
- FGF signaling patterns cell fate at the interface between tendon and bone
Summary: FGF signaling is essential in establishing the graded transitional tissue of the tendon-bone attachment unit by regulating cell fate decisions and the development of Scx+/Sox9+ cells.
- Migrating cells control morphogenesis of substratum serving as track to promote directional movement of the collective
Summary: Collectively migrating cells not only respond to extrinsic molecular cues and surrounding topology, but can also physically modify the morphogenesis of their tissue substrate.
- A dual function of FGF signaling in Xenopus left-right axis formation
Summary: FGF signaling induces and patterns the frog left-right organizer in the early gastrula and regulates the morphogenesis of the flow sensor following specification of the precursor tissue.
- Wnt/Fgf crosstalk is required for the specification of basal cells in the mouse trachea
Summary: Wnt proteins from the epithelium control the formation of mouse airway cartilage and basal cells through crosstalk with Fgf signaling.
- Coordinated directional outgrowth and pattern formation by integration of Wnt5a and Fgf signaling in planar cell polarity
Summary: During mouse limb morphogenesis, Wnt5a plays both instructive and permissive roles in regulating planar cell polarity by orienting PCP itself, and by allowing apical ectoderm ridge-derived Fgfs to orient PCP.
- Fibroblast growth factors: key players in regeneration and tissue repair
Summary: This Review summarizes the roles of fibroblast growth factors in repair and regeneration of different tissues and organs and in different organisms, ranging from planarians to humans.
- Suppression of ERK signalling abolishes primitive endoderm formation but does not promote pluripotency in rabbit embryo
Highlighted Article: A comprehensive analysis of rabbit preimplantation development reveals key differences between rabbit and mouse, with some aspects of lineage specification in rabbit more closely resembling that of human and primate embryos.
- Convergence of signaling pathways underlying habenular formation and axonal outgrowth in zebrafish
Summary: Development of dHb neurons and posteriorly directed outgrowth of their axons are regulated by Shh, Wnt, Fgf, and chemokine signaling pathways in zebrafish.