Interneurons
- Coup-TF1 and Coup-TF2 control subtype and laminar identity of MGE-derived neocortical interneurons
Summary: The regulation of somatostatin (SST) and parvalbumin (PV) mouse cortical interneurons is mediated by Coup-TF1- and Coup-TF2-driven Sox6 expression, identifying a transcriptional pathway that controls SST-PV fate.
- Transcription factors COUP-TFI and COUP-TFII are required for the production of granule cells in the mouse olfactory bulb
Summary: The proliferation, migration and survival of a subpopulation of olfactory bulb interneurons is regulated by COUP-TFI and COUP-TFII, two transcription factors expressed in the SVZ-RMS-OB system.