JNK signaling
- The membrane protein Raw regulates dendrite pruning via the secretory pathway
Summary: A novel and JNK-independent role of the membrane protein Raw is revealed in regulating the secretory pathway and thereby promoting dendrite pruning in Drosophila.
- Apoptosis restores cellular density by eliminating a physiologically or genetically induced excess of enterocytes in the Drosophila midgut
Highlighted article: Ingestion of low amounts of bacteria induces a mild early stress response that triggers the proliferation of Drosophila midgut stem cells, with excess cells then eliminated by apoptosis.
- Trithorax regulates systemic signaling during Drosophila imaginal disc regeneration
Summary: The chromatin modifier Trithorax regulates a negative feedback loop that controls JNK signaling and Insulin-like Peptide 8 expression in damaged Drosophila imaginal discs.