Laminin
- Laminin α2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development
Summary: The proliferation and survival of midbrain dopaminergic neurons is regulated by laminin α2, mutations in which can cause abnormalities in dopaminergic neuron number.
- Characterization of Drosophila Nidogen/entactin reveals roles in basement membrane stability, barrier function and nervous system patterning
Summary: Characterization of Drosophila Nidogen/Entactin (Ndg) mutants reveals that Ndg is not essential for basement membrane (BM) assembly but its loss impaired BM stability and permeability, and caused peripheral nervous system defects.
- Influence of ovarian muscle contraction and oocyte growth on egg chamber elongation in Drosophila
Summary: Contraction of the ovarian muscles helps to produce the elongated shape of the Drosophila egg by stimulating yolk uptake by the oocyte.
- Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages
Highlighted article: In the zebrafish fin, a Wnt gradient dictates the expression of laminin α5, which signals via integrin α3 to control epithelial cell morphology.