Morpholino
- Tek (Tie2) is not required for cardiovascular development in zebrafish
Summary: Mouse Tek mutants and zebrafish tek morphants display severe defects but zebrafish tek mutants do not; we show that tek morpholinos cause off-target effects and that tek is missing in most fish.
- Functional evidence that Activin/Nodal signaling is required for establishing the dorsal-ventral axis in the annelid Capitella teleta
Summary: Morpholino knockdown experiments in the annelid Capitella teleta demonstrate that the dorsal-ventral axis is primarily patterned by the Activin/Nodal pathway of the TGF-β superfamily, rather than by the BMP pathway.