Neural tube defects
- Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation
Summary: A folate receptor-dependent action promotes neural tube formation by facilitating the changes in neural plate cell shape that are required during neurulation.
- Neural tube closure: cellular, molecular and biomechanical mechanisms
Summary: This Review discusses the cellular, molecular and biomechanical mechanisms involved in neural tube closure, focusing on the most recent advances in the field.
- Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development
Highlighted article: Fat1-Fat4 dimer formation is proposed to bring together diverse proteins at apical junctions to regulate both apical constriction and progenitor cell divisions in the neural tube.