Neuroendocrine
- The fenestrae-associated protein Plvap regulates the rate of blood-borne protein passage into the hypophysis
Summary: Fenestrae play a principal role in regulation of homeostasis. The fenestral protein Plvap regulates the rate of plasma protein entry from the general circulation into the brain parenchyma.
- Revising the embryonic origin of thyroid C cells in mice and humans
Highlighted article: Mouse thyroid C cell precursors arise in foregut endoderm, and not the neural crest, disproving the current concept of a neural crest origin of thyroid neuroendocrine cells.