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Parvalbumin

  • REVIEW
    Cortical interneuron development: a tale of time and space
    Jia Sheng Hu, Daniel Vogt, Magnus Sandberg, John L. Rubenstein
    Development 2017 144: 3867-3878; doi: 10.1242/dev.132852

    Summary: This Review examines new insights into cortical GABAergic interneuron subtype specification, focussing on spatial, temporal and genetic mechanisms regulating cell fate decisions in the mouse medial ganglionic eminence.

  • RESEARCH ARTICLE
    Coup-TF1 and Coup-TF2 control subtype and laminar identity of MGE-derived neocortical interneurons
    Jia Sheng Hu, Daniel Vogt, Susan Lindtner, Magnus Sandberg, Shanni N. Silberberg, John L. R. Rubenstein
    Development 2017 144: 2837-2851; doi: 10.1242/dev.150664

    Summary: The regulation of somatostatin (SST) and parvalbumin (PV) mouse cortical interneurons is mediated by Coup-TF1- and Coup-TF2-driven Sox6 expression, identifying a transcriptional pathway that controls SST-PV fate.

  • STEM CELLS AND REGENERATION
    Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells
    Jennifer A. Tyson, Ethan M. Goldberg, Asif M. Maroof, Qing Xu, Timothy J. Petros, Stewart A. Anderson
    Development 2015 142: 1267-1278; doi: 10.1242/dev.111526

    Summary: Mimicking development, production of parvalbumin versus somatostatin cortical interneurons from embryonic stem cells can be controlled just by modulating culture duration and exposure to sonic hedgehog.

  • RESEARCH ARTICLES
    A crucial role for polysialic acid in developmental interneuron migration and the establishment of interneuron densities in the mouse prefrontal cortex
    Tim Kröcher, Iris Röckle, Ute Diederichs, Birgit Weinhold, Hannelore Burkhardt, Yuchio Yanagawa, Rita Gerardy-Schahn, Herbert Hildebrandt
    Development 2014 141: 3022-3032; doi: 10.1242/dev.111773

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