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Prox1

  • RESEARCH ARTICLE
    YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling
    Boksik Cha, Yen-Chun Ho, Xin Geng, Md. Riaj Mahamud, Lijuan Chen, Yeunhee Kim, Dongwon Choi, Tae Hoon Kim, Gwendalyn J. Randolph, Xinwei Cao, Hong Chen, R. Sathish Srinivasan
    Development 2020 147: dev195453 doi: 10.1242/dev.195453 Published 13 December 2020

    Summary: YAP and TAZ mediate the positive feedback loop between PROX1 and VEGF-C signaling in the developing lymphatic and lymphovenous valves.

  • RESEARCH ARTICLE
    A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development
    Cathy Pichol-Thievend, Kelly L. Betterman, Xiaolei Liu, Wanshu Ma, Renae Skoczylas, Emmanuelle Lesieur, Frank L. Bos, Dorte Schulte, Stefan Schulte-Merker, Benjamin M. Hogan, Guillermo Oliver, Natasha L. Harvey, Mathias Francois
    Development 2018 145: dev160184 doi: 10.1242/dev.160184 Published 17 May 2018

    Highlighted Article: Genetic lineage tracing and targeted gene disruption and gain of function identify a novel source of lymphatic endothelial progenitors that contribute to the formation of lymphatic vasculature in mouse skin.

  • RESEARCH ARTICLE
    Molecular control of two novel migratory paths for CGE-derived interneurons in the developing mouse brain
    Audrey Touzot, Nuria Ruiz-Reig, Tania Vitalis, Michèle Studer
    Development 2016 143: 1753-1765; doi: 10.1242/dev.131102

    Highlighted article: Migrating interneurons reach their targets not only via the well-established caudal route, but also via rostrally directed streams that require the COUP-TF nuclear receptors.

  • RESEARCH ARTICLES
    Divergence of zebrafish and mouse lymphatic cell fate specification pathways
    Andreas van Impel, Zhonghua Zhao, Dorien M. A. Hermkens, M. Guy Roukens, Johanna C. Fischer, Josi Peterson-Maduro, Henricus Duckers, Elke A. Ober, Philip W. Ingham, Stefan Schulte-Merker
    Development 2014 141: 1228-1238; doi: 10.1242/dev.105031
  • STEM CELLS AND REGENERATION
    Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment
    Asha Seth, Jianming Ye, Nanjia Yu, Fanny Guez, David C. Bedford, Geoffrey A. Neale, Sabine Cordi, Paul K. Brindle, Frederic P. Lemaigre, Klaus H. Kaestner, Beatriz Sosa-Pineda
    Development 2014 141: 538-547; doi: 10.1242/dev.099481
  • RESEARCH ARTICLES
    Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium
    Aino Murtomaki, Minji K. Uh, Yun K. Choi, Christopher Kitajewski, Valeriya Borisenko, Jan Kitajewski, Carrie J. Shawber
    Development 2013 140: 2365-2376; doi: 10.1242/dev.083865

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