Pruning
- The membrane protein Raw regulates dendrite pruning via the secretory pathway
Summary: A novel and JNK-independent role of the membrane protein Raw is revealed in regulating the secretory pathway and thereby promoting dendrite pruning in Drosophila.
- NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann–Pick disease type C
Summary: Genetic deficiency of Npc1 impairs postnatal development of microglia and climbing fiber synaptic pruning in the mouse cerebellum.
- Yif1 associates with Yip1 on Golgi and regulates dendrite pruning in sensory neurons during Drosophila metamorphosis
Summary: Two novel Drosophila proteins, Yif1 and Yip1, associate with each other and regulate Golgi integrity to act as novel players of dendrite pruning in sensory neurons during early metamorphosis.
- Spatial regulation of microtubule disruption during dendrite pruning in Drosophila
Summary: Kinesin-dependent uniform plus-end-in microtubule organization is required for efficient c4da neuron microtubule breakdown and dendrite pruning in the Drosophila PNS during early pupal phase.
- Sec71 functions as a GEF for the small GTPase Arf1 to govern dendrite pruning of Drosophila sensory neurons
Summary: The Arf1/Sec71-dependent secretory pathway governs Golgi integrity and dendrite pruning in Drosophila sensory neurons.
- Cell behaviors and dynamics during angiogenesis
Summary: This Review discusses endothelial cell behavior during developmental angiogenesis, focusing on the morphogenetic changes that these cells undergo.