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Retinoic acid

  • STEM CELLS AND REGENERATION
    Retinoic acid receptor regulation of epimorphic and homeostatic regeneration in the axolotl
    Matthew Nguyen, Pankhuri Singhal, Judith W. Piet, Sandra J. Shefelbine, Malcolm Maden, S. Randal Voss, James R. Monaghan
    Development 2017 144: 601-611; doi: 10.1242/dev.139873

    Summary: A unique transcriptional program that regulates the coordination of positional information and tissue differentiation in regenerating salamander limbs and tails .

  • RESEARCH ARTICLE
    Retinoid signaling controls spermatogonial differentiation by regulating expression of replication-dependent core histone genes
    Yao Chen, Li Ma, Cathryn Hogarth, Gang Wei, Michael D. Griswold, Ming-Han Tong
    Development 2016 143: 1502-1511; doi: 10.1242/dev.135939

    Highlighted article: Upregulation of replication-dependent core histone genes by retinoic acid signaling contributes to spermatogonial differentiation in mice.

  • RESEARCH ARTICLE
    Retinoic acid-induced premature osteoblast-to-preosteocyte transitioning has multiple effects on calvarial development
    Shirine Jeradi, Matthias Hammerschmidt
    Development 2016 143: 1205-1216; doi: 10.1242/dev.129189

    Summary: Increased RA levels in developing zebrafish have multiple effects on skull formation, ranging from gain to loss of bone, and depending on allelic strength, developmental stage and cellular context.

  • STEM CELLS AND REGENERATION
    Antagonism between Gdf6a and retinoic acid pathways controls timing of retinal neurogenesis and growth of the eye in zebrafish
    Leonardo E. Valdivia, Dayna B. Lamb, Wilson Horner, Claudia Wierzbicki, Amanuel Tafessu, Audrey M. Williams, Gaia Gestri, Anna M. Krasnow, Terra S. Vleeshouwer-Neumann, McKenzie Givens, Rodrigo M. Young, Lisa M. Lawrence, Heather L. Stickney, Thomas A. Hawkins, Quenten P. Schwarz, Florencia Cavodeassi, Stephen W. Wilson, Kara L. Cerveny
    Development 2016 143: 1087-1098; doi: 10.1242/dev.130922

    Summary: In the vertebrate eye, dorsally expressed Gdf6a limits RA pathway activity to control the transition from proliferation to differentiation, thereby regulating eye size.

  • RESEARCH REPORT
    Retinoic acid signaling regulates development of the dorsal forebrain midline and the choroid plexus in the chick
    Sandeep Gupta, Jonaki Sen
    Development 2015 142: 1293-1298; doi: 10.1242/dev.122390

    Summary: In the chick embryo, retinoic acid signaling controls the invagination of the forebrain roof plate and exerts a negative influence on choroid plexus development.

  • RESEARCH ARTICLE
    Retinoic acid regulates size, pattern and alignment of tissues at the head-trunk transition
    Keun Lee, Isaac Skromne
    Development 2014 141: 4375-4384; doi: 10.1242/dev.109603
  • RESEARCH ARTICLES
    A regulatory network controls nephrocan expression and midgut patterning
    Juan Hou, Wei Wei, Ranajeet S. Saund, Ping Xiang, Thomas J. Cunningham, Yuyin Yi, Olivia Alder, Daphne Y. D. Lu, Joanne G. A. Savory, Nicole A. J. Krentz, Rachel Montpetit, Rebecca Cullum, Nicole Hofs, David Lohnes, R. Keith Humphries, Yojiro Yamanaka, Gregg Duester, Yukio Saijoh, Pamela A. Hoodless
    Development 2014 141: 3772-3781; doi: 10.1242/dev.108274
  • RESEARCH REPORTS
    Retinoic acid controls body axis extension by directly repressing Fgf8 transcription
    Sandeep Kumar, Gregg Duester
    Development 2014 141: 2972-2977; doi: 10.1242/dev.112367
  • STEM CELLS AND REGENERATION
    Cyp26 enzymes are required to balance the cardiac and vascular lineages within the anterior lateral plate mesoderm
    Ariel B. Rydeen, Joshua S. Waxman
    Development 2014 141: 1638-1648; doi: 10.1242/dev.105874
  • RESEARCH ARTICLES
    Diffusible signals and epigenetic timing cooperate in late proximo-distal limb patterning
    Alberto Roselló-Díez, Carlos G. Arques, Irene Delgado, Giovanna Giovinazzo, Miguel Torres
    Development 2014 141: 1534-1543; doi: 10.1242/dev.106831

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