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Semaphorin 3A

  • RESEARCH ARTICLE
    Alteration of Nrp1 signaling at different stages of olfactory neuron maturation promotes glomerular shifts along distinct axes in the olfactory bulb
    Alexis Assens, Julien A. Dal Col, Anthony Njoku, Quentin Dietschi, Chenda Kan, Paul Feinstein, Alan Carleton, Ivan Rodriguez
    Development 2016 143: 3817-3825; doi: 10.1242/dev.138941

    Summary: During olfactory bulb development in mice, different axonal targeting outcomes are dependent on the timing of Nrp1/Sema3A signaling.

  • RESEARCH REPORT
    Endothelial cell-derived semaphorin 3A inhibits filopodia formation by blood vascular tip cells
    Alexandra M. Ochsenbein, Sinem Karaman, Steven T. Proulx, Michaela Berchtold, Giorgia Jurisic, Esther T. Stoeckli, Michael Detmar
    Development 2016 143: 589-594; doi: 10.1242/dev.127670

    Summary: Endothelial cells produce Sema3A, a known axon repellent, that exerts repelling functions on VEGF-A-induced tip cell filopodia during angiogenesis in mice.

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