SMAD4
- Smad4-dependent morphogenic signals control the maturation and axonal targeting of basal vomeronasal sensory neurons to the accessory olfactory bulb
Summary: Genetic disruption of TGFβ/BMP signaling in maturing basal vomeronasal sensory neurons (VSNs) or in all mature VSNs indicates that Smad4 signaling drives maturation and connectivity of basal VSNs.
- Dual function of Bmpr1a signaling in restricting preosteoblast proliferation and stimulating osteoblast activity in mouse
Summary: The genetic deletion of Bmpr1a in mice reveals a dual function for BMP signaling in restricting preosteoblast proliferation and promoting osteoblast activity, probably via regulation of mTORC1.