Tailbud
- Neuromesodermal progenitors are a conserved source of spinal cord with divergent growth dynamics
Highlighted Article: A complete lineage analysis of neuromesodermal progenitors in zebrafish through a combination of genetic clonal labelling, forward fate mapping and in toto imaging.
- FGF and canonical Wnt signaling cooperate to induce paraxial mesoderm from tailbud neuromesodermal progenitors through regulation of a two-step epithelial to mesenchymal transition
Summary: FGF signaling is required for post-gastrula paraxial mesoderm induction through a unique mechanism that differs from its role during gastrula stage mesoderm induction.
- The zebrafish tailbud contains two independent populations of midline progenitor cells that maintain long-term germ layer plasticity and differentiate in response to local signaling cues
Summary: Progenitor cells that generate the midline tissues of the zebrafish floor plate, notochord, and hypochord make germ layer decisions after gastrulation based on local canonical Wnt and Notch signaling.