Yolk syncytial layer
- A cargo model of yolk syncytial nuclear migration during zebrafish epiboly
Summary: Microtubule motor proteins kinesin and dynein directly carry yolk syncytial nuclei along microtubules towards the vegetal pole, mediated by the LINC complex, which acts as an adaptor between nuclei and motor proteins.
- The primary role of zebrafish nanog is in extra-embryonic tissue
Highlighted Article: Detailed analyses of zebrafish nanog mutants, including tissue-specific rescue and chimera analysis, indicate that Nanog is necessary for yolk syncytial layer development but is not directly required for embryonic cell differentiation.